TY - JOUR
T1 - Effects of COVID-19 Infection on Spermatogenesis, Oxidative Stress and Erectile Function
AU - Törzsök, P.
AU - Oswald, D.
AU - Steiner, C.
AU - Abenhardt, M.
AU - Ramesmayer, C.
AU - Milinovic, L.
AU - Plank, B.
AU - Tischleritsch, Z.
AU - Lusuardi, L.
AU - Deininger, S.
N1 - Export Date: 14 December 2023
Correspondence Address: Törzsök, P.; Department of Urology and Andrology, Austria; email: [email protected]
Funding details: Paracelsus Medizinische Privatuniversität, PMU
Funding text 1: This research was supported by the Department of Urology and Andrology, Salzburg University Hospital, Paracelsus Medical University, Austria.
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Urol, 19, pp. 423-436. , 34552795; https://covid19.who.int/info, Available onlineUR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85178135385&doi=10.3390%2fjcm12227099&partnerID=40&md5=5d3c7c77f922e1524052b88524018577
PY - 2023/11/15
Y1 - 2023/11/15
N2 - Background: Our aim was to evaluate the effect of COVID-19 infection on male fertility and sexual function. Methods: Thirty-one patients were investigated over a mean follow-up of 90 days (22–527) after a COVID-19 infection. Erectile dysfunction (ED), blood tests for sexual hormones, semen analysis including analysis of oxidative stress (OS), as well as COVID-19 antibody titer and the nasal COVID-19 PCR test were evaluated pre- and post-infection. Results: Five patients reported a mild de novo ED (16.13%). One patient had a de novo positive mixed antiglobulin reaction test after the infection. We found no significant difference between pre-COVID-19 and post-COVID-19 spermiogram parameters (p = 0.815). OS showed no significant association with COVID-19 infection, but with pathological spermiogram categories, sperm concentration, total sperm count, testis volume, FSH and testosterone. Conclusion: COVID-19 infection does not appear to affect sperm quality and OS negatively in the intermediate term. Further investigations will be needed to assess the potential long-term effects of the infection and vaccination on male sexual function and fertility.
AB - Background: Our aim was to evaluate the effect of COVID-19 infection on male fertility and sexual function. Methods: Thirty-one patients were investigated over a mean follow-up of 90 days (22–527) after a COVID-19 infection. Erectile dysfunction (ED), blood tests for sexual hormones, semen analysis including analysis of oxidative stress (OS), as well as COVID-19 antibody titer and the nasal COVID-19 PCR test were evaluated pre- and post-infection. Results: Five patients reported a mild de novo ED (16.13%). One patient had a de novo positive mixed antiglobulin reaction test after the infection. We found no significant difference between pre-COVID-19 and post-COVID-19 spermiogram parameters (p = 0.815). OS showed no significant association with COVID-19 infection, but with pathological spermiogram categories, sperm concentration, total sperm count, testis volume, FSH and testosterone. Conclusion: COVID-19 infection does not appear to affect sperm quality and OS negatively in the intermediate term. Further investigations will be needed to assess the potential long-term effects of the infection and vaccination on male sexual function and fertility.
KW - COVID-19
KW - infection
KW - male fertility
KW - oxidative stress
KW - semen analysis
KW - testosterone
KW - virus
UR - https://www.mendeley.com/catalogue/d1f4af93-5833-3f43-9f43-e539b2eee81a/
U2 - 10.3390/jcm12227099
DO - 10.3390/jcm12227099
M3 - Article
C2 - 38002711
SN - 2077-0383
VL - 12
JO - J. Clin. Med.
JF - J. Clin. Med.
IS - 22
ER -
SDG 3 Good Health and Well-being